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Striatal neuronal loss correlates with clinical motor impairment in Huntington’s disease

BACKGROUND: Huntington disease is characterized clinically by chorea, motor impairment, psychiatric manifestations and dementia. Atrophy of the striatum is the neuropathological hallmark of Huntington disease and previous studies have suggested that striatal atrophy correlates more closely with moto...

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Detalhes bibliográficos
Main Authors: Guo, Zhihong, Rudow, Gay, Pletnikova, Olga, Codispoti, Kari-Elise, Orr, Brent A., Crain, Barbara J., Duan, Wenzhen, Margolis, Russell L., Rosenblatt, Adam, Ross, Christopher A., Troncoso, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455126/
https://ncbi.nlm.nih.gov/pubmed/22975850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25159
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