Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies

BACKGROUND: We have previously established aberrant DNA methylation of Vimentin exon-1 (VIM methylation) as a common epigenetic event in colon cancer and as a biomarker for detecting colon neoplasia. We now examine VIM methylation in neoplasia of the upper gastrointestinal tract. METHODS: Using a qu...

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Hlavní autoři: Moinova, Helen, Leidner, Rom S., Ravi, Lakshmeswari, Lutterbaugh, James, Barnholtz-Sloan, Jill S., Chen, Yanwen, Chak, Amitabh, Markowitz, Sanford D., Willis, Joseph E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454489/
https://ncbi.nlm.nih.gov/pubmed/22315367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-1060
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