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Adoptive Immunotherapy with Cl-IB-MECA-Treated CD8+ T Cells Reduces Melanoma Growth in Mice

Cl-IB-MECA is a selective A3 adenosine receptor agonist, which plays a crucial role in limiting tumor progression. In mice, Cl-IB-MECA administration enhances the anti-tumor T cell-mediated response. However, little is known about the activity of Cl-IB-MECA on CD8+ T cells. The aim of this study was...

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Detalhes bibliográficos
Main Authors: Montinaro, Antonella, Forte, Giovanni, Sorrentino, Rosalinda, Luciano, Antonio, Palma, Giuseppe, Arra, Claudio, Adcock, Ian M., Pinto, Aldo, Morello, Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454429/
https://ncbi.nlm.nih.gov/pubmed/23028986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045401
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