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The adenosinergic system in cancer: Key therapeutic target

High amounts of adenosine are released in the tumor mass. Depending on the levels of adenosine, as well as on the receptor subtypes that are expressed by immune cells, adenosine can affect tumor growth in different fashions. Specifically targeting CD73, the rate-limiting enzyme for the extracellular...

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Bibliografiske detaljer
Main Authors: Sorrentino, Rosalinda, Pinto, Aldo, Morello, Silvana
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583919/
https://ncbi.nlm.nih.gov/pubmed/23483072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22448
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