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Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma
CD73 is a cell surface enzyme that suppresses T-cell mediated immune responses, by producing extracellular adenosine. Increasing evidence suggest that targeting CD73 in cancer may be useful for an effective therapeutic outcome. Here, we demonstrate that administration of a specific CD73 inhibitor, A...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442235/ https://ncbi.nlm.nih.gov/pubmed/22826317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200744 |
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