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Regulation of bacterial DNA supercoiling: plasmid linking numbers vary with growth temperature.

The level of DNA supercoiling can be altered either by breaking-rejoining reactions that change the DNA linking number or by environmental changes that alter the helical pitch of DNA. In vitro, temperature changes alter helical pitch and, thus, supercoiling. We find that plasmids isolated from bacte...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Goldstein, E, Drlica, K
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6377307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.13.4046
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