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Analysis of the transforming potential of the human H-ras gene by random mutagenesis.
Some tumor cells contain mutant ras genes that are capable of transforming NIH 3T3 cells. Those genes that have been analyzed arise from the wild-type, non-transforming ras genes by mutations producing single amino acid substitutions at position 12 or 61 of the encoded protein. We have performed ran...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6330729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.13.4008 |
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