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Analysis of the transforming potential of the human H-ras gene by random mutagenesis.

Some tumor cells contain mutant ras genes that are capable of transforming NIH 3T3 cells. Those genes that have been analyzed arise from the wild-type, non-transforming ras genes by mutations producing single amino acid substitutions at position 12 or 61 of the encoded protein. We have performed ran...

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Bibliografiska uppgifter
Huvudupphovsmän: Fasano, O, Aldrich, T, Tamanoi, F, Taparowsky, E, Furth, M, Wigler, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1984
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC345357/
https://ncbi.nlm.nih.gov/pubmed/6330729
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