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The relevance of apolipoprotein E polymorphism to Alzheimer's disease
The apo E gene located on chromosome 19 in humans is polymorphic. The three apo E isoforms E2, E3, and E4 are coded by three common alleles of the gene. The amyloid plaques in brains of Alzheimer disease (AD) patients are known to contain apo E. There is an increased prevalence of E4 allele in AD pa...
保存先:
| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer India
1999
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3453560/ https://ncbi.nlm.nih.gov/pubmed/23105201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF02869150 |
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