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Effect of apolipoprotein E (APO E) polymorphism on leptin in Alzheimer's disease
BACKGROUND: Leptin, a 16 kDa peptide hormone synthesized and secreted specifically from white adipose cells protects neurons against amyloid β-induced toxicity, by increasing Apolipoprotein E (APO E)-dependent uptake of β amyloid into the cells, thereby, protect individuals from developing Alzheimer...
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| Publié dans: | Ann Indian Acad Neurol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Medknow Publications & Media Pvt Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564468/ https://ncbi.nlm.nih.gov/pubmed/26425011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0972-2327.157255 |
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