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Effect of apolipoprotein E (APO E) polymorphism on leptin in Alzheimer's disease

BACKGROUND: Leptin, a 16 kDa peptide hormone synthesized and secreted specifically from white adipose cells protects neurons against amyloid β-induced toxicity, by increasing Apolipoprotein E (APO E)-dependent uptake of β amyloid into the cells, thereby, protect individuals from developing Alzheimer...

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Detalhes bibliográficos
Publicado no:Ann Indian Acad Neurol
Main Authors: Agarwal, Rachna, Talwar, Puneet, Kushwaha, Suman S., Tripathi, Chandra Bhushan, Kukreti, Ritushree
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564468/
https://ncbi.nlm.nih.gov/pubmed/26425011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0972-2327.157255
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