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The relevance of apolipoprotein E polymorphism to Alzheimer's disease
The apo E gene located on chromosome 19 in humans is polymorphic. The three apo E isoforms E2, E3, and E4 are coded by three common alleles of the gene. The amyloid plaques in brains of Alzheimer disease (AD) patients are known to contain apo E. There is an increased prevalence of E4 allele in AD pa...
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| Glavni autor: | |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer India
1999
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3453560/ https://ncbi.nlm.nih.gov/pubmed/23105201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF02869150 |
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