DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

A temperature-sensitive DNA topoisomerase II mutant of the yeast Saccharomyces cerevisiae has been identified. Genetic analysis shows that a single recessive nuclear mutation is responsible for both temperature-sensitive growth and enzymatic activity. Thus, topoisomerase II is essential for viabilit...

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Detalles Bibliográficos
Main Authors: DiNardo, S, Voelkel, K, Sternglanz, R
Formato: Artigo
Idioma:Inglês
Publicado: 1984
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC345120/
https://ncbi.nlm.nih.gov/pubmed/6326134
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