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DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

A temperature-sensitive DNA topoisomerase II mutant of the yeast Saccharomyces cerevisiae has been identified. Genetic analysis shows that a single recessive nuclear mutation is responsible for both temperature-sensitive growth and enzymatic activity. Thus, topoisomerase II is essential for viabilit...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: DiNardo, S, Voelkel, K, Sternglanz, R
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1984
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6326134/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.9.2616
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