Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.

Mammalian cells express two genetically distinct isoforms of DNA topoisomerase II, designated topoisomerase IIalphaand topoisomerase IIbeta. We have recently shown that mouse topoisomerase IIalpha can substitute for the yeast topoisomerase II enzyme and complement yeast top2 mutations. This function...

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Detaylı Bibliyografya
Yayımlandı:	Nucleic Acids Res
Asıl Yazarlar:	Adachi, N, Miyaike, M, Kato, S, Kanamaru, R, Koyama, H, Kikuchi, A
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Oxford University Press 1997
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9224616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.15.3135
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Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.

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