Antibody against the insulin receptor causes disappearance of insulin receptors in 3T3-L1 cells: a possible explanation of antibody-induced insulin resistance.
The effect of a rabbit antibody induced against the rat insulin receptor (RAR) was tested using cultured 3T3-L1 fat cells. As previously seen with antibodies against the insulin receptor from patients with the type B syndrome of insulin resistance and acanthosis nigricans, RAR acutely mimicked the a...
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| 發表在: | Proc Natl Acad Sci U S A |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1984
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6371815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.8.2508 |
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