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Antibody against the insulin receptor causes disappearance of insulin receptors in 3T3-L1 cells: a possible explanation of antibody-induced insulin resistance.

The effect of a rabbit antibody induced against the rat insulin receptor (RAR) was tested using cultured 3T3-L1 fat cells. As previously seen with antibodies against the insulin receptor from patients with the type B syndrome of insulin resistance and acanthosis nigricans, RAR acutely mimicked the a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Grunfeld, C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6371815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.8.2508
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