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Expression of immunoglobulin heavy chain at a high level in the absence of a proposed immunoglobulin enhancer element in cis.

The major intron between the J and C gene segments of the immunoglobulin heavy (H) chain locus contains an enhancer-like sequence, and it has been proposed that this enhancer is necessary to achieve high levels of H chain expression. We have isolated a subclone of the lymphoid pre-B cell line 18-81...

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Autors principals: Wabl, M R, Burrows, P D
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC345079/
https://ncbi.nlm.nih.gov/pubmed/6326129
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