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Expression of immunoglobulin heavy chain at a high level in the absence of a proposed immunoglobulin enhancer element in cis.

The major intron between the J and C gene segments of the immunoglobulin heavy (H) chain locus contains an enhancer-like sequence, and it has been proposed that this enhancer is necessary to achieve high levels of H chain expression. We have isolated a subclone of the lymphoid pre-B cell line 18-81...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Wabl, M R, Burrows, P D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1984
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6326129/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.8.2452
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