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Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

Previous theoretical considerations and some experimental data have suggested a role for DNA methylation in the maintenance of mammalian X chromosome inactivation. The isolation of specific X-encoded sequences makes it possible to investigate this hypothesis directly. We have used cloned fragments o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yen, P H, Patel, P, Chinault, A C, Mohandas, T, Shapiro, L J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324214/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.6.1759
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