Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.
Previous theoretical considerations and some experimental data have suggested a role for DNA methylation in the maintenance of mammalian X chromosome inactivation. The isolation of specific X-encoded sequences makes it possible to investigate this hypothesis directly. We have used cloned fragments o...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.6.1759 |
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