Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

Previous theoretical considerations and some experimental data have suggested a role for DNA methylation in the maintenance of mammalian X chromosome inactivation. The isolation of specific X-encoded sequences makes it possible to investigate this hypothesis directly. We have used cloned fragments o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yen, P H, Patel, P, Chinault, A C, Mohandas, T, Shapiro, L J
Format: Artigo
Langue:Inglês
Publié: 1984
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC344999/
https://ncbi.nlm.nih.gov/pubmed/6324214
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