Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

Previous theoretical considerations and some experimental data have suggested a role for DNA methylation in the maintenance of mammalian X chromosome inactivation. The isolation of specific X-encoded sequences makes it possible to investigate this hypothesis directly. We have used cloned fragments o...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Yen, P H, Patel, P, Chinault, A C, Mohandas, T, Shapiro, L J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.6.1759
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