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Computer simulations of enzyme catalysis: Finding out what has been optimized by evolution

The origin of the catalytic power of enzymes is discussed, paying attention to evolutionary constraints. It is pointed out that enzyme catalysis reflects energy contributions that cannot be determined uniquely by current experimental approaches without augmenting the analysis by computer simulation...

詳細記述

保存先:
書誌詳細
主要な著者: Warshel, Arieh, Florián, Jan
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC34499/
https://ncbi.nlm.nih.gov/pubmed/9600897
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