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Modulation of cell cycle progression and of antibody production in mouse hybridomas by a nucleotide analogue

The nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG) has been identified as a powerful antiproliferative substance when acting on hybridoma cells. In the range of 10 nM to 100 nM concentrations this agent reduces cell growth rate, while its apoptosis-inducing activity is marginal. Mar...

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Detalhes bibliográficos
Main Authors: Franěk, František, Holý, Antonín, Votruba, Ivan, Eckschlager, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449840/
https://ncbi.nlm.nih.gov/pubmed/19003408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008017328061
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