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Aliphatic analogues of nucleotides: synthesis and affinity towards nucleases

DL-1-(2,3-Dihydroxypropyl)thymine was prepared by Hilbert-Johnson reaction of 2,4-dinethoxy-5-methylpyrimidine with allyl bromide followed by the osmium tetroxide catalyzed hydroxylation of the l-allyl-4-methoxy-5-methylpyrimidin-2-one obtained as an intermediate. The D-glycero enantiomer, R-1-(2,3-...

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Dettagli Bibliografici
Autori principali: Holý, A., Ivanova, G.S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1974
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC343320/
https://ncbi.nlm.nih.gov/pubmed/10793656
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