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Aliphatic analogues of nucleotides: synthesis and affinity towards nucleases
DL-1-(2,3-Dihydroxypropyl)thymine was prepared by Hilbert-Johnson reaction of 2,4-dinethoxy-5-methylpyrimidine with allyl bromide followed by the osmium tetroxide catalyzed hydroxylation of the l-allyl-4-methoxy-5-methylpyrimidin-2-one obtained as an intermediate. The D-glycero enantiomer, R-1-(2,3-...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1974
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC343320/ https://ncbi.nlm.nih.gov/pubmed/10793656 |
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