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Aliphatic analogues of nucleotides: synthesis and affinity towards nucleases
DL-1-(2,3-Dihydroxypropyl)thymine was prepared by Hilbert-Johnson reaction of 2,4-dinethoxy-5-methylpyrimidine with allyl bromide followed by the osmium tetroxide catalyzed hydroxylation of the l-allyl-4-methoxy-5-methylpyrimidin-2-one obtained as an intermediate. The D-glycero enantiomer, R-1-(2,3-...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1974
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC343320/ https://ncbi.nlm.nih.gov/pubmed/10793656 |
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