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Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture

An analog of aromatic cytokinins, the 2,6,9-trisubstituted purine derivative bohemine, was applied to cultures of mouse hybridoma cells in order to analyze its capacity of suppressing cell growth and maintaining or enhancing the production of monoclonal antibody. Addition of bohemine at concentratio...

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Detalhes bibliográficos
Main Authors: Franěk, František, Strnad, Miroslav, Havlíček, Libor, Siglerová, Věra, Fismolová, Ivana, Eckschlager, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449669/
https://ncbi.nlm.nih.gov/pubmed/19003322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1014020415912
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