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Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture

An analog of aromatic cytokinins, the 2,6,9-trisubstituted purine derivative bohemine, was applied to cultures of mouse hybridoma cells in order to analyze its capacity of suppressing cell growth and maintaining or enhancing the production of monoclonal antibody. Addition of bohemine at concentratio...

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Bibliographic Details
Main Authors: Franěk, František, Strnad, Miroslav, Havlíček, Libor, Siglerová, Věra, Fismolová, Ivana, Eckschlager, Tomáš
Format: Artigo
Language:Inglês
Published: Kluwer Academic Publishers 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449669/
https://ncbi.nlm.nih.gov/pubmed/19003322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1014020415912
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