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Characterisation of BHK-21 cells engineered to secrete human insulin

Autoimmune destruction of β cells in the pancreas leads to type I, or insulin dependent diabetes mellitus (IDDM), through the loss of endogenous insulin production capacity. This paper describes an attempt to generate ‘artificial’β cells using the fibroblast cell line BHK21. Stable transfectants exp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gammell, Patrick, O'Driscoll, Lorraine, Clynes, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Kluwer Academic Publishers 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449758/
https://ncbi.nlm.nih.gov/pubmed/19002958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1024296220592
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