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Characterisation of BHK-21 cells engineered to secrete human insulin

Autoimmune destruction of β cells in the pancreas leads to type I, or insulin dependent diabetes mellitus (IDDM), through the loss of endogenous insulin production capacity. This paper describes an attempt to generate ‘artificial’β cells using the fibroblast cell line BHK21. Stable transfectants exp...

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Autori principali: Gammell, Patrick, O'Driscoll, Lorraine, Clynes, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Kluwer Academic Publishers 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449758/
https://ncbi.nlm.nih.gov/pubmed/19002958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1024296220592
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