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Characterisation of BHK-21 cells engineered to secrete human insulin

Autoimmune destruction of β cells in the pancreas leads to type I, or insulin dependent diabetes mellitus (IDDM), through the loss of endogenous insulin production capacity. This paper describes an attempt to generate ‘artificial’β cells using the fibroblast cell line BHK21. Stable transfectants exp...

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Detalhes bibliográficos
Main Authors: Gammell, Patrick, O'Driscoll, Lorraine, Clynes, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449758/
https://ncbi.nlm.nih.gov/pubmed/19002958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1024296220592
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