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Caspase activation, sialidase release and changes in sialylation pattern of recombinant human erythropoietin produced by CHO cells in batch and fed-batch cultures

The activation of caspases represents a crucial turning point during a batch or a fed-batch culture of mammalian cells. It not only affects the quantity but also the quality of the recombinant glycoprotein produced. In this study, the activation of various caspases, the release of intracellular sial...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chuan, Kok Hwee, Lim, Sing Fee, Martin, Laurent, Yun, Chee Yong, Loh, Sophia O. H., Lasne, Francoise, Song, Zhiwei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Kluwer Academic Publishers 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449677/
https://ncbi.nlm.nih.gov/pubmed/19002897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-006-9016-5
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