Primary Role of the Chromophore Bond Length Alternation in Reversible Photoconversion of Red Fluorescence Proteins

Rapid photobleaching of fluorescent proteins can limit their use in imaging applications. The underlying kinetics is multi-exponential and strongly depends on the local chromophore environment. The first, reversible, step may be attributed to a rotation around one of the two exocyclic C-C bonds brid...

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Main Authors: Drobizhev, Mikhail, Hughes, Thomas E., Stepanenko, Yuriy, Wnuk, Pawel, O'Donnell, Kieran, Scott, J. Nathan, Callis, Patrik R., Mikhaylov, Alexander, Dokken, Leslie, Rebane, Aleksander
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449290/
https://ncbi.nlm.nih.gov/pubmed/23008753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00688
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