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Primary Role of the Chromophore Bond Length Alternation in Reversible Photoconversion of Red Fluorescence Proteins

Rapid photobleaching of fluorescent proteins can limit their use in imaging applications. The underlying kinetics is multi-exponential and strongly depends on the local chromophore environment. The first, reversible, step may be attributed to a rotation around one of the two exocyclic C-C bonds brid...

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Detalhes bibliográficos
Main Authors: Drobizhev, Mikhail, Hughes, Thomas E., Stepanenko, Yuriy, Wnuk, Pawel, O'Donnell, Kieran, Scott, J. Nathan, Callis, Patrik R., Mikhaylov, Alexander, Dokken, Leslie, Rebane, Aleksander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449290/
https://ncbi.nlm.nih.gov/pubmed/23008753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00688
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