Toll-like receptor 4 knockout protects against anthrax lethal toxin-induced cardiac contractile dysfunction: role of autophagy

BACKGROUND AND PURPOSE: Anthrax lethal toxin (LeTx) is known to induce circulatory shock and death, although the underlying mechanisms have not been elucidated. This study was designed to evaluate the role of toll-like receptor 4 (TLR4) in anthrax lethal toxin-induced cardiac contractile dysfunction...

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Bibliographic Details
Main Authors: Kandadi, Machender R, Frankel, Arthur E, Ren, Jun
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449265/
https://ncbi.nlm.nih.gov/pubmed/22612289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02040.x
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