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Targeted inhibition of Src kinase signaling attenuates pancreatic tumorigenesis

Elevated Src expression correlates with malignant potential and metastatic disease in many tumors including pancreas cancer. We sought to characterize the molecular effects of Src kinase inhibition with dasatinib (BMS-354825) a novel, multi-targeted kinase inhibitor that targets Src family kinases,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Nagaraj, Nagathihalli S., Smith, J. Joshua, Revetta, Frank, Washington, M. Kay, Merchant, Nipun B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449211/
https://ncbi.nlm.nih.gov/pubmed/20682659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-1212
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