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Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokines

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the synovial joints, deformities, and disability. The prolonged use of conventional anti-inflammatory drugs is associated with severe adverse effects. Therefore, there is an urgent need for safer and less exp...

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Main Authors: Venkatesha, Shivaprasad H., Astry, Brian C., Nanjundaiah, Siddaraju M., Yu, Hua, Moudgil, Kamal D.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449088/
https://ncbi.nlm.nih.gov/pubmed/22854193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.06.050
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