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Celastrus and Its Bioactive Celastrol Protect against Bone Damage in Autoimmune Arthritis by Modulating Osteoimmune Cross-talk

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by bone erosion and cartilage destruction in the joints. Many of the conventional antiarthritic drugs are effective in suppressing inflammation, but they do not offer protection against bone damage. Furthermore, the prolonged...

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Bibliographic Details
Main Authors: Nanjundaiah, Siddaraju M., Venkatesha, Shivaprasad H., Yu, Hua, Tong, Li, Stains, Joseph P., Moudgil, Kamal D.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381183/
https://ncbi.nlm.nih.gov/pubmed/22549786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356816
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