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Activities of DNA base excision repair enzymes in liver and brain correlate with body mass, but not lifespan
Accumulation of DNA lesions compromises replication and transcription and is thus toxic to cells. DNA repair deficiencies are generally associated with cellular replicative senescence and premature aging syndromes, suggesting that efficient DNA repair is required for normal longevity. It follows tha...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449000/ https://ncbi.nlm.nih.gov/pubmed/21853261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9302-9 |
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