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Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.

When arachidonic acid was incubated with homogenates of potato tubers, two isomers of 6-trans-leukotriene B4, epimeric at C-12, were formed in addition to the major product, (5S-hydroperoxy-6-trans-8,11,14-cis-icosatetraenoic acid (5-HPETE). To elucidate the mechanism of biosynthesis of the dihydrox...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Shimizu, T, Rådmark, O, Samuelsson, B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1984
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6322165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.3.689
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