Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.
When arachidonic acid was incubated with homogenates of potato tubers, two isomers of 6-trans-leukotriene B4, epimeric at C-12, were formed in addition to the major product, (5S-hydroperoxy-6-trans-8,11,14-cis-icosatetraenoic acid (5-HPETE). To elucidate the mechanism of biosynthesis of the dihydrox...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6322165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.3.689 |
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