Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen.

Lignende værker

• Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation.
  af: Carmichael, G G, et al.
  Udgivet: (1982)
• Polyoma middle-sized T antigen can be phosphorylated on tyrosine at multiple sites in vitro.
  af: Hunter, T, et al.
  Udgivet: (1984)
• The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation.
  af: Mes-Masson, A M, et al.
  Udgivet: (1984)
• A polyoma mutant that encodes small T antigen but not middle T antigen demonstrates uncoupling of cell surface and cytoskeletal changes associated with cell transformation.
  af: Liang, T J, et al.
  Udgivet: (1984)
• Lessons from Polyoma Middle T Antigen on Signaling and Transformation: A DNA Tumor Virus Contribution to the War on Cancer
  af: Schaffhausen, Brian S., et al.
  Udgivet: (2008)