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Rituximab mediates loss of CD19 on B cells in the absence of cell death
OBJECTIVE: To evaluate loss of the B cell specific marker CD19 with addition of rituximab (RTX) to healthy donor blood and to determine the role of complement mediated cytotoxicity in these cells. METHODS: Healthy donor whole blood and peripheral blood mononuclear cells (PBMC) were evaluated for los...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448861/ https://ncbi.nlm.nih.gov/pubmed/22674374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34560 |
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