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Rituximab induces Interleukin-6 production by human B cells

OBJECTIVE: Rituximab (RTX), an anti-CD20 monoclonal antibody, is highly effective in the treatment of several autoimmune diseases. The mechanism by which RTX treatment improves Rheumatoid Arthritis and ANCA-Associated Vasculitis is not easily related to B cell depletion. We have shown that RTX media...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jones, Jonathan D., Hamilton, B. JoNell, Skopelja, Sladjana, Rigby, William F. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211955/
https://ncbi.nlm.nih.gov/pubmed/25080282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38798
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