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Rituximab induces Interleukin-6 production by human B cells

OBJECTIVE: Rituximab (RTX), an anti-CD20 monoclonal antibody, is highly effective in the treatment of several autoimmune diseases. The mechanism by which RTX treatment improves Rheumatoid Arthritis and ANCA-Associated Vasculitis is not easily related to B cell depletion. We have shown that RTX media...

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Detalhes bibliográficos
Main Authors: Jones, Jonathan D., Hamilton, B. JoNell, Skopelja, Sladjana, Rigby, William F. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211955/
https://ncbi.nlm.nih.gov/pubmed/25080282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38798
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