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NK cells are required for co-stimulatory blockade induced tolerance to vascularized allografts

BACKGROUND: The role of natural killer (NK) cells in organ transplantation is poorly understood as studies link these cells to both regulatory and inflammatory functions. NK cells exacerbate inflammation and adaptive immunity under conditions of allograft rejection, but little is known regarding the...

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Main Authors: van der Touw, William, Burrell, Bryna, Lal, Girdhari, Bromberg, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448808/
https://ncbi.nlm.nih.gov/pubmed/22914174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318264d3c4
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