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T Helper Cells Fate Mapping by Co-stimulatory Molecules and its Functions in Allograft Rejection and Tolerance

T cell differentiation is dictated by a combination of T cell receptor (TCR) interaction with an antigen-bound major histocompatibility complex (MHC), and co-stimulatory molecules signal. The co-stimulatory signal can be positive or negative, and amplifying or diminishing the initial signal. However...

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Detalhes bibliográficos
Main Authors: Abdoli, R., Najafian, N.
Formato: Artigo
Idioma:Inglês
Publicado em: Avicenna Organ Transplantation Institute 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149737/
https://ncbi.nlm.nih.gov/pubmed/25184030
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