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X-ray structures of magnesium and manganese complexes with the N-terminal domain of calmodulin: Insights into the mechanism and specificity of metal ion binding to an EF-hand
Calmodulin (CaM), a member of the EF-hand superfamily, regulates many aspects of the cell function by responding specifically to micromolar concentrations of Ca(2+) in the presence of ~1000× higher concentration of cellular Mg(2+). To explain the structural basis of metal ion binding specificity we...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448793/ https://ncbi.nlm.nih.gov/pubmed/22803592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300698h |
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