Solution Structure of the Na(V)1.2 C-terminal EF-hand Domain

Voltage-gated sodium channels initiate the rapid upstroke of action potentials in many excitable tissues. Mutations within intracellular C-terminal sequences of specific channels underlie a diverse set of channelopathies, including cardiac arrhythmias and epilepsy syndromes. The three-dimensional st...

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Detalhes bibliográficos
Main Authors: Miloushev, Vesselin Z., Levine, Joshua A., Arbing, Mark A., Hunt, John F., Pitt, Geoffrey S., Palmer, Arthur G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649098/
https://ncbi.nlm.nih.gov/pubmed/19129176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807401200
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