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Morphine Decreases Enteric Neuron Excitability via Inhibition of Sodium Channels

Gastrointestinal peristalsis is significantly dependent on the enteric nervous system. Constipation due to reduced peristalsis is a major side-effect of morphine, which limits the chronic usefulness of this excellent pain reliever in man. The ionic basis for the inhibition of enteric neuron excitabi...

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Main Authors: Smith, Tricia H., Grider, John R., Dewey, William L., Akbarali, Hamid I.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448635/
https://ncbi.nlm.nih.gov/pubmed/23028881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045251
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