Sensitization of enteric neurons to morphine by HIV-1 Tat protein

BACKGROUND: Gastrointestinal (GI) dysfunction is a major cause of morbidity in AIDS. HIV-1-induced neuropathogenesis is significantly enhanced by opiate abuse, which increases proinflammatory chemokine/cytokine release, the production of reactive species, glial reactivity, and neuronal injury in the...

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Publicat a:Neurogastroenterol Motil
Autors principals: Fitting, Sylvia, Ngwainmbi, Joy, Kang, Minho, Khan, Fayez A., Stevens, David L., Dewey, William L., Knapp, Pamela E., Hauser, Kurt F., Akbarali, Hamid I.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380805/
https://ncbi.nlm.nih.gov/pubmed/25703354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12514
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