Focal Adhesion Kinase Plays a Role in Osteoblast Mechanotransduction In Vitro but Does Not Affect Load-Induced Bone Formation In Vivo

A healthy skeleton relies on bone's ability to respond to external mechanical forces. The molecular mechanisms by which bone cells sense and convert mechanical stimuli into biochemical signals, a process known as mechanotransduction, are unclear. Focal adhesions play a critical role in cell sur...

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Détails bibliographiques
Auteurs principaux: Castillo, Alesha B., Blundo, Jennifer T., Chen, Julia C., Lee, Kristen L., Yereddi, Nikitha Reddy, Jang, Eugene, Kumar, Shefali, Tang, W. Joyce, Zarrin, Sarah, Kim, Jae-Beom, Jacobs, Christopher R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448625/
https://ncbi.nlm.nih.gov/pubmed/23028449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043291
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